THE EFFECT OF pH ON THE PERMEABILITY OF COLLODION MEMBRANES COATED WITH PROTEIN

نویسنده

  • David I. Hitchcock
چکیده

The permeability of gelatin-coated collodion membranes, as measured by the flow of water or of dilute solutions through the membranes, has been found to vary with the pH of the solutions. The permeability is greatest near the isoelectric point of the protein; with increasing concentration of either acid or alkali it decreases, passes through a minimum, and then increases. These variations with pH are qualitatively in accord with the assumption that they are due to swelling of the gelatin in the pores of the membrane, the effects of pH being similar to those observed by Loeb on the swelling of gelatin granules. Indications have been found of a similar variable permeability in the case of membranes coated with egg albumin, edestin, serum euglobulin, and serum albumin.

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

THE EFFECT OF pH ON THE PERMEABILITY OF COLLODION MEMBRANES COATED WITH PROTEIN

In a study of some of the factors affecting the formation of protein films on collodion membranes,' it was found that the amounts of protein adhering to the membranes varied with the pH in a way similar, in the case of gelatin, to the variation of the fluidity of the protein solutions with the pH. The connection between the viscosity of gelatin solutions and the swelling of gelatin particles ha...

متن کامل

Protein Films on Collodion Membranes

1. Collodion membranes of high permeability were found to adsorb weighable amounts of gelatin and egg albumin from solution at 37 degrees C. 2. The effect of protein concentration could be expressed fairly well by a hyperbolic equation proposed by Langmuir for the adsorption of gases by a plane surface, while the usual parabolic adsorption equation of Freundlich did not fit the results. 3. In c...

متن کامل

The Adsorption of Gelatin by Collodion Membranes

An experimental study has been made of the adsorption of gelatin from solution at 37 degrees C. by collodion membranes. In the case of membranes of high permeability, very high concentrations of gelatin were required to produce maximum adsorption, and the maximum amounts adsorbed were independent of the pH values of the solutions over the range 3.8 to 4.8. With membranes of low permeability, ma...

متن کامل

THE STRUCTURE OF T H E COLLODION MEMBRANE AND ITS ELECTRICAL BEHAVIOR XII. THE PP~PARATION AND PROPERTIES OF "MEGAPERMSELECTIVE" PROTAMnCE COLLODION MEMBRANES

The preceding paper 1 of this series describes the preparation of "megapermselective" collodion membranes which are extremely impermeable to anions, but at the same time are very permeable to univalent cations. The purpose of the present paper is to describe the preparation and the properties of analogous electropositive "megapermselecfive" membranes which are very impermeable to cations, but a...

متن کامل

The effect of polar copolymers in protein absorption on contact lenses on 2-Hydroxyethyl methacrylate(HEMA)

For the purpose of increasing the permeability to oxygen and equilibrium water content in contact lenses, polar copolymers with nonionic monomers such as 2-hydroxyethle methacrylate(HEMA) Is used. By adding the polar monomers to (HEMA), the permeability to oxygen and equilibrium with water content is increased and also the absorption of proteins on lens surface is changed. In this research, the...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:
  • The Journal of General Physiology

دوره 10  شماره 

صفحات  -

تاریخ انتشار 2003